K579
K579 is a potent and orally active dipeptidyl peptidase IV inhibitor. K579 inhibits the blood glucose elevation. K579 increases the plasma insulin and active forms of glucagon-like peptide-1 (GLP-1) . K579 has the potential for the research of diabetic[1].
Product Specifications
CAS Number
[440100-64-1]
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/k579.html
Purity
99.19
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
N#C[C@H]1N(C(CNC2(C)CCN(C3=NC=CC=N3)CC2)=O)CCC1
Molecular Formula
C17H24N6O
Molecular Weight
328.41
References & Citations
[1]Takasaki K, et al. K579, a slow-binding inhibitor of dipeptidyl peptidase IV, is a long-acting hypoglycemic agent. Eur J Pharmacol. 2004 Feb 23;486 (3) :335-42.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4
Available Sizes
Curated Selection
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