AGPS-IN-1
AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells[1].
Product Specifications
CAS Number
[2316782-88-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/agps-in-1.html
Purity
99.74
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1NC2=CC=C(CNC(CC(C)C3=C(F)C=CC=C3F)=O)C=C2N1
Molecular Formula
C18H17F2N3O2
Molecular Weight
345.34
Precautions
H302, H315, H319
References & Citations
[1]Stazi G, et al. Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells. Eur J Med Chem. 2019 Feb 1;163:722-735.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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