RBN012759
RBN012759 is a potent, selective and orally active inhibitor of PARP14, with an IC50 of [1].
Product Specifications
CAS Number
2360851-29-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rbn012759.html
Purity
99.33
Solubility
DMSO : 233.33 mg/mL (ultrasonic)
Smiles
O=C1NC(CS[C@H]2CC[C@H](O)CC2)=NC3=C1C(F)=CC(OCC4CC4)=C3
Molecular Formula
C19H23FN2O3S
Molecular Weight
378.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Schenkel L, et, al. A potent and selective PARP14 inhibitor decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants. AACR Annual Meeting 2020.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP10; PARP14; PARP4; PARP7
Available Sizes
Frequently Asked Questions
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