Anthracene-9-carboxylic acid

Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[1].

Product Specifications

CAS Number

[723-62-6]

Product Name Alternative

9-Anthracenecarboxylic acid

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Chloride Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/anthracene-9-carboxylic-acid.html

Purity

99.09

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=C2C=CC=CC2=CC3=CC=CC=C13)O

Molecular Formula

C15H10O2

Molecular Weight

222.24

Precautions

H315, H319

References & Citations

[1]Cherian OL, Menini A, Boccaccio A. Multiple effects of anthracene-9-carboxylic acid on the TMEM16B/anoctamin2 calcium-activated chloride channel. Biochim Biophys Acta. 2015 Apr;1848 (4) :1005-13.|[2]Piper AS, Greenwood IA. Anomalous effect of anthracene-9-carboxylic acid on calcium-activated chloride currents in rabbit pulmonary artery smooth muscle cells. Br J Pharmacol. 2003 Jan;138 (1) :31-8.