Illudin M

Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities[1][2].

Product Specifications

CAS Number

[1146-04-9]

UNSPSC

12352211

Target

Apoptosis; DNA Alkylator/Crosslinker

Type

Natural Products

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/illudin-m.html

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=CC(C)([C@@H](C2=C(C3([C@@]1(C)O)CC3)C)O)C

Molecular Formula

C15H20O3

Molecular Weight

248.32

References & Citations

[1]Rainer Schobert, et al. Conjugates of the fungal cytotoxin illudin M with improved tumour specificity. Bioorg Med Chem. 2008 Sep 15;16 (18) :8592-7.|[2]Dr. Philipp Le, et al. A Chemical Proteomic Analysis of Illudin‐Interacting Proteins. Chemistry. 2019 Sep 25; 25 (54) : 12644–12651.