Human Neuropilin-2a Extracellular Domain (recombinant)

<strong>Human Neuropilin-2a Extracellular Domain (recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2016778_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 95 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Vascular Endothelial Cell Growth Factor165 Receptor 2a, VEGF165 Receptor 2a_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Dimou A, Nasarre C, Peterson YK, Pagano R, Gooz M, Nasarre P, Drabkin HA, Armeson KE, Gibney BC, Gemmill RM, Denlinger CE. Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer J Thorac Cardiovasc Surg. 2021 Aug;162(2):463-473._x000D_ 2: Dhupar R, Jones KE, Powers AA, Eisenberg SH, Ding K, Chen F, Nasarre C, Cen Z, Gong YN, LaRue AC, Yeh ES, Luketich JD, Lee AV, Oesterreich S, Lotze MT, Gemmill RM, Soloff AC. Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer Front Immunol. 2022 Apr 27;13:830169._x000D_ 3: Hermans K, Claes F, Vandevelde W, Zheng W, Geudens I, Orsenigo F, De Smet F, Gjini E, Anthonis K, Ren B, Kerjaschki D, Autiero M, Ny A, Simons M, Dewerchin M, Schulte-Merker S, Dejana E, Alitalo K, Carmeliet P. Role of synectin in lymphatic development in zebrafish and frogs Blood. 2010 Oct 28;116(17):3356-66._x000D_ 4: Barton R, Palacio D, Iovine MK, Berger BW. A cytosolic juxtamembrane interface modulates plexin A3 oligomerization and signal transduction PLoS One. 2015 Jan 7;10(1):e0116368._x000D_ 5: Cantuti-Castelvetri L, Ojha R, Pedro LD, Djannatian M, Franz J, Kuivanen S, van der Meer F, Kallio K, Kaya T, Anastasina M, Smura T, Levanov L, Szirovicza L, Tobi A, Kallio-Kokko H, Österlund P, Joensuu M, Meunier FA, Butcher SJ, Winkler MS, Mollenhauer B, Helenius A, Gokce O, Teesalu T, Hepojoki J, Vapalahti O, Stadelmann C, Balistreri G, Simons M. Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity Science. 2020 Nov 13;370(6518):856-860._x000D_ 6: Niland S, Eble JA. Neuropilin: Handyman and Power Broker in the Tumor Microenvironment Adv Exp Med Biol. 2020;1223:31-67._x000D_ 7: Broz M, Kolarič A, Jukič M, Bren U. Neuropilin (NRPs) Related Pathological Conditions and Their Modulators Int J Mol Sci. 2022 Jul 29;23(15):8402._x000D_ 8: Mercurio AM. VEGF/Neuropilin Signaling in Cancer Stem Cells Int J Mol Sci. 2019 Jan 23;20(3):490._x000D_ 9: Benedicto A, García-Kamiruaga I, Arteta B. Neuropilin-1: A feasible link between liver pathologies and COVID-19 World J Gastroenterol. 2021 Jun 28;27(24):3516-3529._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30315890">10: Peng K, Bai Y, Zhu Q, Hu B, Xu Y. Targeting VEGF-neuropilin interactions: a promising antitumor strategy Drug Discov Today. 2019 Feb;24(2):656-664. </a>_x000D_ _x000D_ <strong>Products Related to Human Neuropilin-2a Extracellular Domain (recombinant) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>