Withaferin A
Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
Product Specifications
CAS Number
5119-48-2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Ferroptosis; NF-κB
Type
Natural Products
Related Pathways
Apoptosis; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Withaferin_A.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@]([C@](CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@@H]([C@@](O3)([H])CC(C)=C(CO)C3=O)C)([H])[C@@]2([H])C4)(C(C=C5)=O)[C@@]6([C@H]5O)[C@@H]4O6
Molecular Formula
C28H38O6
Molecular Weight
470.60
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Phospho-Dab1 (Tyr198) Rabbit Polyclonal Antibody (PE-Cy7)
Flt3 Ligand Human Recombinant, Sf9 (Flt3 Ligand Human, Sf9)
Flt3 Ligand Human Recombinant, Sf9 (Flt3 Ligand Human, Sf9)
Flt3 Ligand Human Recombinant, Sf9 (Flt3 Ligand Human, Sf9)
