8-OH-cAMP
8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases[1].
Product Specifications
CAS Number
31356-95-3
Product Name Alternative
8-Hydroxy-cAMP
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/8-oh-camp.html
Smiles
O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C(O)=NC4=C3N=CN=C4N
Molecular Formula
C10H12N5O7P
Molecular Weight
345.21
References & Citations
[1]Waidmann O, et al. Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8- (4-chlorophenylthio) -modified cAMP analogs and their hydrolytic products[J]. Journal of biological chemistry, 2009, 284 (47) : 32256-32263.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRC-P319903-1G 1 g
4,4'-(1,4-Phenylenebis(ethene-2,1-diyl))dibenzonitrile
Sign In for Pricing
View Details 