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3-Cyanoumbelliferone

3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki of 2.9 μM[1].

Product Specifications

CAS Number

[19088-73-4]

UNSPSC

12171500

Hazard Statement

H302, H312, H315, H319, H332, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-cyanoumbelliferone.html

Purity

98.0

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC1=CC2=CC=C(O)C=C2OC1=O

Molecular Formula

C10H5NO3

Molecular Weight

187.15

Precautions

H302, H312, H315, H319, H332, H335

References & Citations

[1]Orita M, et al. Coumarin and chromen-4-one analogues as tautomerase inhibitors of macrophage migration inhibitory factor: discovery and X-ray crystallography. J Med Chem. 2001 Feb 15;44 (4) :540-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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