ARTD3/PARP3-IN-1
ARTD3/PARP3-IN-1 is an unselective inhibitor of diphtheria toxin-like ADP-ribosyltransferase 3 (ARTD3) /PARP3[1].
Product Specifications
CAS Number
[730949-09-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/artd3-parp3-in-1.html
Purity
99.64
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N=C(CCC(NCC2=NC=CC=C2)=O)NC3=C1C=CC=C3
Molecular Formula
C17H16N4O2
Molecular Weight
308.33
Precautions
H302, H315, H319
References & Citations
[1]Lindgren AE, et al. Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3. J Med Chem. 2013 Dec 12;56 (23) :9556-68. |[2]Lindgren AE, et al. Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3. J Med Chem. 2013 Dec 12;56 (23) :9556-68.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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