Polyinosinic-polycytidylic acid (potassium)
Polyinosinic-polycytidylic acid potassium (Poly (I:C) potassium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I) -like receptors (RIG-I and MDA5) . Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid potassium can directly trigger cancer cells to undergoApoptosis[1][2][3].
Product Specifications
CAS Number
31852-29-6
Product Name Alternative
Poly (I:C) (potassium)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/polyinosinic-polycytidylic-acid-potassium.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C3=C(C(N=CN3)=O)N=C2.O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]4N5C(N=C(C=C5)N)=O.[x].[x]
Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xK
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR3
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Insulin (2D11-H5), CF640R conjugate, 0.1mg/mL
Cytokeratin 17 (E3), CF594 conjugate, 0.1mg/mL
CD50 / ICAM3 (CG106), CF488A conjugate, 0.1mg/mL
