HEK293/Human GIPR Stable Cell Line (Medium Expression)
HEK293/Human GIPR Stable Cell Line (Medium Expression) is expressed from Human HEK293.
Product Specifications
Background
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2012]
Host
HEK293
Origin Species
Human
Target
GIPR
Applications
• Useful for cell-based GIPR binding assay • Screen for human GIPR agonists based on cAMP accumulation assay
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
HEK293
Species
Human
Curated Selection
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