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HEK293/Human GIPR Stable Cell Line (Medium Expression)

HEK293/Human GIPR Stable Cell Line (Medium Expression) is expressed from Human HEK293.

Product Specifications

Background

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2012]

Host

HEK293

Origin Species

Human

Target

GIPR

Applications

• Useful for cell-based GIPR binding assay • Screen for human GIPR agonists based on cAMP accumulation assay

Format

Liquid

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

Frozen in liquid nitrogen

Package Size

1Vial*2

Host or Source

HEK293

Species

Human

Frequently Asked Questions

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