CP-447697
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation[1].
Product Specifications
CAS Number
1092847-21-6
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cp-447697.html
Purity
99.70
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC(C=C1)=CC=C1CCN(C(C2=CSC3=C2C=CC=C3)=O)C4CCN(C(NC5=CC=C(F)C=C5F)=O)CC4
Molecular Formula
C29H26ClF2N3O2S
Molecular Weight
554.05
References & Citations
[1]Blagg J, et al. Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett. 2008 Oct 15;18 (20) :5601-4.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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