Migoprotafib
Product Specifications
UNSPSC Description
Migoprotafib (GDC-1971) (compound 199) is a SHP2 inhibitor[1].
Target Antigen
Phosphatase; SHP2
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-gdc-1971.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N[C@H]1C2(CCN(C3=CN=C(C(N4C5=CC=CN=C5CCC4)=NN6)C6=N3)CC2)OC7=CC=CC=C71
Molecular Weight
454.53
References & Citations
[1]Alexander M, et al. Shp2 phosphatase inhibitors and methods of use thereof. Patent WO2019183367A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144903/Migoprotafib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144903/Migoprotafib-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
2377352-49-1
Available Sizes
Curated Selection
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