APC Conjugated Anti-Mouse CD8 alpha Recombinant Antibody [PSH05-00] - Rabbit IgG (Chimeric)
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen-presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Cd8a, Lyt-2, Lyt2
Swiss Prot
P01731 Mouse
Cellular Locus
Cell membrane.
Species Reactivity
Mouse
Immunogen
Recombinant protein.
Isotype
IgG
Clone
PSH05-00
Conjugation
APC
Type
Recombinant Chimeric Antibody Antibody
Applications
FC
Positive Control
BABL/C mouse splenocytes.
Dilution
FC: 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.
Molecular Weight
Predicted band size: 27 kDa
Storage Conditions
Store at 2°C to 8°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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