Human Glypican 3 / GPC3 (S359F) Protein, His Tag, low endotoxin (MALS verified)

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.7 kDa. The protein migrates as 31 kDa, 43 kDa and 66-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P51654-1 (S359F)

Expression Region

Gln 25 - His 559

Host

HEK293

Target

Glypican 3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.01 EU per μg

Purity

90%

Bioactivity

Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 0.5 μg/mL (100 μL/well) can bind Human Glypican 3 (S359F), His Tag (Cat. No. GP3-H52H7) with a linear range of 20-156 ng/mL (QC tested).