Isocurcumenol
Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively[1][2].
Product Specifications
CAS Number
24063-71-6
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Estrogen Receptor/ERR
Type
Natural Products
Related Pathways
Apoptosis; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isocurcumenol.html
Purity
99.47
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@]1(C2)/C(C[C@]3(O1)[C@@H](C)CC[C@@]3([H])C2=C)=C(C)/C
Molecular Formula
C15H22O2
Molecular Weight
234.33
Precautions
H302
References & Citations
[1]Lakshmi S, et al. Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. Int J Med Chem. 2011;2011:253962.|[2]Resmi Mustarichiei, et al. In silico study of curcumol, curcumenol, isocurcumenol, and β-sitosterol as potential inhibitors of estrogen receptor alpha of breast cancer. Basic Medical Research. 2014
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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