Guaifenesin-d3

Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].

Product Specifications

CAS Number

[1189924-85-3]

Product Name Alternative

Guaiacol glyceryl ether-d3; Guaiphenesin-d3; Glycerol guaiacolate-d3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Inflammation/Immunology; Neurological Disease

Purity

99.00

Solubility

10 mM in DMSO|DMF : ≥ 30mg/mL|DMSO : ≥ 30mg/mL|Ethanol : ≥ 15mg/mL

Smiles

OCC(O)COC1=C(C=CC=C1)OC([2H])([2H])[2H]

Molecular Formula

C10H11D3O4

Molecular Weight

201.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Bennett, S., N. Hoffman, and M. Monga, Ephedrine- and guaifenesin-induced nephrolithiasis. J Altern Complement Med, 2004. 10 (6) : p. 967-9.|[3]Dicpinigaitis PV, et, al. Effect of guaifenesin on cough reflex sensitivity. Chest. 2003 Dec;124 (6) :2178-81.