1,3,6-Tri-O-galloyl-beta-D-glucose

1,3,6-Tri-O-galloyl-beta-D-glucose is a non-covalent inhibitor of tyrosinase (TYR), which can block the rate-limiting step of melanin synthesis and inhibit melanin deposition. 1,3,6-Tri-O-galloyl-beta-D-glucose has antioxidant and anti-inflammatory activities and can be used as a natural active ingredient to develop anti-freckle and whitening skin care products[1].

Product Specifications

CAS Number

[18483-17-5]

Product Name Alternative

1,3,6-Tri-O-galloyl-β-D-glucose

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1-3-6-tri-o-galloyl-beta-d-glucose.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC(O)=C(O)C(O)=C1)O[C@@H]2[C@H]([C@@H](O[C@H](COC(C3=CC(O)=C(O)C(O)=C3)=O)[C@H]2O)OC(C4=CC(O)=C(O)C(O)=C4)=O)O

Molecular Formula

C27H24O18

Molecular Weight

636.47

Precautions

H315, H319, H335

References & Citations

[1]Li L, et al. Mechanism of skin whitening through San-Bai decoction-induced tyrosinase inhibition and discovery of natural products targeting tyrosinase. Medicine (Baltimore) . 2023 Mar 31;102 (13) :e33420.