Melanotan (MT) -II
Melanotan (MT) -II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.
Product Specifications
CAS Number
121062-08-6
UNSPSC
12352209
Hazard Statement
H315-H319-H335
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Melanotan__MT_-II.html
Purity
99.97
Solubility
H2O : 6.67 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@@](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CCCC)=O)CC(NCCCC[C@](C(N)=O)([H])NC1=O)=O)=O)CC2=CN=CN2)=O)([H])CC3=CC=CC=C3)=O)CCCNC(N)=N)N[C@H]1CC4=CNC5=CC=CC=C45
Molecular Formula
C50H69N15O9
Molecular Weight
1024.18
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7 (2) :164-72.|[2]Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138 (1) :293-301.|[3]Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462 (1-3) :179-83.|[4]Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9.|[5]De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303 (5) :E644-51.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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