Melanotan (MT) -II

Melanotan (MT) -II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

Product Specifications

CAS Number

[121062-08-6]

UNSPSC

12352209

Hazard Statement

H315-H319-H335

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Melanotan__MT_-II.html

Purity

99.97

Solubility

H2O : 6.67 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@@](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CCCC)=O)CC(NCCCC[C@](C(N)=O)([H])NC1=O)=O)=O)CC2=CN=CN2)=O)([H])CC3=CC=CC=C3)=O)CCCNC(N)=N)N[C@H]1CC4=CNC5=CC=CC=C45

Molecular Formula

C50H69N15O9

Molecular Weight

1024.18

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7 (2) :164-72.|[2]Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138 (1) :293-301.|[3]Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462 (1-3) :179-83.|[4]Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9.|[5]De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303 (5) :E644-51.