Formoterol-1

Formoterol ((±) Formoterol) is an orally active β2-selective agonist. Formoterol potently relaxes the peripheral airways through stimulating the beta 2-adrenoceptors selectively as is the case in the central airways and that it significantly inhibits IgE-mediated slow reactive substance of anaphylaxis (SRS-A) release through beta-adrenoceptor stimulation[1].

Product Specifications

CAS Number

[73573-87-2]

Product Name Alternative

(±) Formoterol

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/formoterol-1.html

Purity

99.84

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=CNC1=CC([C@H](O)CN[C@@H](C)CC2=CC=C(OC)C=C2)=CC=C1O.[relativestereochemistry]

Molecular Formula

C19H24N2O4

Molecular Weight

344.40

Precautions

H302, H315, H319, H335

References & Citations

[1]Tomioka K, et al. Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats. Arch Int Pharmacodyn Ther. 1984;267 (1) :91-102.