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HPK1-IN-2 (dihydrochloride)

HPK1-IN-2 dihydrochloride is a potent and orally active hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50IC50IC50[1].

Product Specifications

CAS Number

2375595-72-3

UNSPSC

12352005

Target

FLT3; MAP4K; Src

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hpk1-in-2-dihydrochloride.html

Concentration

10mM

Purity

97.09

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)

Smiles

O=C1C(C2=NC3=CC=C(N4CCN(C)CC4)C=C3N2)=C(N)C(C=CS5)=C5N1.[H]Cl.[H]Cl

Molecular Formula

C19H22Cl2N6OS

Molecular Weight

453.39

References & Citations

[1]Peter Brent Sampson, et al. Hpk1 inhibitors and methods of using same. WO2016205942A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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