Methyl paraben-d4

Methyl paraben-d4 is the deuterium labeled Methyl Paraben[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].

Product Specifications

CAS Number

[362049-51-2]

Product Name Alternative

Methyl 4-hydroxybenzoate-d4

UNSPSC

12352005

Hazard Statement

H303, H320, H402, H412

Target

Bacterial; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O=C(OC)C1=C([2H])C([2H])=C(O)C([2H])=C1[2H]

Molecular Formula

C8H4D4O3

Molecular Weight

156.17

Precautions

H303, H320, H402, H412

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Soni MG, et al. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem Toxicol. 2002 Oct;40 (10) :1335-73.