GIP (1-30) amide, human (acetate)

GIP (1-30) amide, human acetate is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) amide, human acetate dose-dependently promotes insulin secretion over the range 10-9-10-6 M[1].

Product Specifications

UNSPSC

12352209

Target

Insulin Receptor

Type

Peptides

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gip-1-30-amide-human-acetate.html

Purity

99.27

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O)CC(C)C)=O)NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC5=CC=C(O)C=C5)N)=O)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)=O)[C@H](CC)C)=O)CO)=O)CC(O)=O)=O)=O)CO)=O)[C@H](CC)C)=O)C)=O)CCSC)=O)CC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CC(O)=O)=O)=O)[C@@H](C)C)=O)CC(N)=O)=O)C=6C=7C(NC6)=CC=CC7.CC(O)=O

Molecular Formula

C164H244N40O49S

Molecular Weight

3591.99

References & Citations

[1]Alaña I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP (1-30) amide. Biochem Biophys Res Commun. 2004 Dec 3;325 (1) :281-6.