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BIO-1211

BIO-1211 is a selective small molecule inhibitor, demonstrating high potency for α4β1 (VLA-4) with an IC50 of 4 nM, while showing significantly lower activity against α4β7 (IC50 = 2 μM) . This selectivity profile makes it a valuable research tool for investigating VLA-4-mediated adhesion and signaling pathways in both cellular and animal models of inflammation and autoimmunity.

Product Specifications

Product Name Alternative

Inhibit, Inhibitor, Integrin, BIO 1211, BIO1211, BIO-1211, α4β1 integrin

Field of Research

Signal Transduction

Purity

99.33% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.05 mM) ; DMSO:250 mg/mL (352.71 mM)

Molecular Weight

708.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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