BIO-1211
BIO-1211 is a selective small molecule inhibitor, demonstrating high potency for α4β1 (VLA-4) with an IC50 of 4 nM, while showing significantly lower activity against α4β7 (IC50 = 2 μM) . This selectivity profile makes it a valuable research tool for investigating VLA-4-mediated adhesion and signaling pathways in both cellular and animal models of inflammation and autoimmunity.
Product Specifications
Product Name Alternative
Inhibit, Inhibitor, Integrin, BIO 1211, BIO1211, BIO-1211, α4β1 integrin
Field of Research
Signal Transduction
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.05 mM) ; DMSO:250 mg/mL (352.71 mM)
Molecular Weight
708.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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