Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

5-A-RU-PABC-Val-Cit-Fmoc

5-A-RU-PABC-Val-Cit-Fmoc is the proagent of 5-A-RU[1]. 5-A-RU, a precursor of bacterial Riboflavin, is a mucosal-associated invariant T (MAIT) cells activator. 5-A-RU forms potent MAIT-activating antigens via non-enzymatic reactions with small molecules, such as glyoxal and methylglyoxal, which are derived from other metabolic pathways[2][3][4].

Product Specifications

CAS Number

2677841-58-4

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-a-ru-pabc-val-cit-fmoc.html

Purity

98.98

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(C=C1)COC(NC2=C(NC(NC2=O)=O)NC[C@@H]([C@@H]([C@@H](CO)O)O)O)=O)[C@@H](NC([C@@H](NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C(C)C)=O)CCCNC(N)=O

Molecular Formula

C43H53N9O13

Molecular Weight

903.93

References & Citations

[1]Joshua Lange, et al. The Chemical Synthesis, Stability, and Activity of MAIT Cell Prodrug Agonists That Access MR1 in Recycling Endosomes. ACS Chem Biol. 2020 Feb 21;15 (2) :437-445.|[2]Corbett AJ, et al. T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature. 2014 May 15;509 (7500) :361-5.|[3]Eckle SB, et al. Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells. J Biol Chem. 2015 Dec 18;290 (51) :30204-11.|[4]Soudais C, et al. In Vitro and In Vivo Analysis of the Gram-Negative Bacteria-Derived Riboflavin PrecursorDerivatives Activating Mouse MAIT Cells. J Immunol. 2015 May 15;194 (10) :4641-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ISOC2 (NM_024710) Human Over-expression Lysate
LY403016 100 µg

ISOC2 (NM_024710) Human Over-expression Lysate

Sign In for Pricing
View Details
Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF488A conjugate, 0.1mg/mL
BNC881782-500 1x 500 µL

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
HA tag, AlpHcAbs® Mouse IgG2a
HA710217 100 µg

HA tag, AlpHcAbs® Mouse IgG2a

Sign In for Pricing
View Details
CD15 / FUT4 (Reed-Sternberg Cell Marker), CF488A conjugate, 0.1mg/mL
BNC881649-100 1x 100 µL

CD15 / FUT4 (Reed-Sternberg Cell Marker), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Tmtc3 Mouse Gene Knockout Kit (CRISPR)
KN517955 1 Kit

Tmtc3 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
FRZB (NM_001463) Human Over-expression Lysate
LC400569 20 µg

FRZB (NM_001463) Human Over-expression Lysate

Sign In for Pricing
View Details