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BQ-123

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC50 of 7.3 nM. This compound is a valuable research tool for investigating the role of ET-1 signaling in cardiovascular diseases, pulmonary hypertension, and cancer, as demonstrated in various in vitro and in vivo studies. It has been evaluated in Phase 2 clinical trials.

Product Specifications

Product Name Alternative

Cells, BQ 123, BQ123, BQ-123, blood, artery, EndothelinReceptor, Endothelin Receptor, Endothelin A receptor, Inhibitor, inhibit, muscle, smooth, pulmonary, pressure

Field of Research

Pharmacology & Drug Discovery

Purity

≥95% (May vary between batches)

Solubility

Ethanol:12 mg/mL (19.65 mM) ; DMSO:93 mg/mL (152.28 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.19 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Molecular Weight

610.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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