Sodium tauroglycocholate

Sodium tauroglycocholate is an inhibitor of the biliary acid transporting system of the hepatocyte and also a surfactant used as a chemical permeation enhancer.

Product Specifications

CAS Number

[41945-48-6]

Product Name Alternative

Tauroglycocholic acid sodium salt

UNSPSC

12352211

Hazard Statement

H302-H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Sodium_tauroglycocholate.html

Concentration

10mM

Solubility

DMSO : 30 mg/mL (ultrasonic; warming)

Smiles

O[C@H](C[C@@](C[C@H](O)CC1)([H])[C@@]1(C)[C@@]2([H])C[C@@H]3O)[C@@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(NCC(NCCS(=O)(O[Na])=O)=O)=O)([H])[C@]34C

Molecular Formula

C28H47N2NaO8S

Molecular Weight

594.74

Precautions

P264-P270-P280-P305+P351+P338-P330-P501

References & Citations

[1]Schuhmann-Giampieri G, et al. Biliary excretion and pharmacokinetics of a gadolinium chelate used as a liver-specific contrast agent for magnetic resonance imaging in the rat. J Pharm Sci. 1993 Aug;82 (8) :799-803.|[2]Kouchak M, et al. Effects of various penetration enhancers on penetration of aminophylline through shed snake skin. Jundishapur J Nat Pharm Prod. 2014 Feb;9 (1) :24-9.