What is the catalog number for TRV-120027 TFA?

The catalog number for TRV-120027 TFA is orb1296359.

What sizes are available for TRV-120027 TFA?

TRV-120027 TFA is available in the following size(s): 1 mg, 5 mg, 10 mg, 1 ml x 10 mM (in DMSO), 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does TRV-120027 TFA come in?

TRV-120027 TFA is available in 8 different pack sizes.

Is TRV-120027 TFA in stock?

TRV-120027 TFA is currently made to order / not held in immediate stock. Contact us for lead time.

TRV-120027 TFA

TRV-120027 TFA is a β-arrestin-biased AT1R agonist that selectively inhibits angiotensin II-mediated G-protein signaling while promoting β-arrestin-1 recruitment. This action inhibits vasoconstriction, enhances cardiomyocyte contractility, and triggers catecholamine secretion via a macromolecular AT1R–β-arrestin-1–TRPC3–PLCγ complex. It is a valuable research tool for studying biased GPCR signaling in cardiovascular physiology and disease models.

Product Specifications

Product Name Alternative

1234510-46-3, 1234510-46-3 free base, AT1 receptor, the angiotensin II receptor type 1, TRP Channel, TRPChannel, TRPV Channel, TRPVChannel, TRV 120027 TFA, TRV120027 TFA, TRV-120027 TFA, TRV-120027 TFA (1234510-46-3 free base)