Fruquintinib (Standard)
Fruquintinib (Standard) is the analytical standard of Fruquintinib. This product is intended for research and analytical applications. Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively.
Product Specifications
CAS Number
1194506-26-7
Product Name Alternative
HMPL-013 (Standard)
UNSPSC
12352005
Target
Reference Standards; VEGFR
Type
Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fruquintinib-standard.html
Purity
99.77
Smiles
O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NC
Molecular Formula
C21H19N3O5
Molecular Weight
393.39
References & Citations
[1]Sun Q, et al. Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy. Cancer Biol Ther. 2014;15 (12) :1635-45.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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