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H3K27 (Me3) (15-34)

H3K27 (Me3) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27 (Me) [1][2].

Product Specifications

UNSPSC

12352209

Target

Histone Methyltransferase

Type

Peptides

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/h3k27-me3-15-34.html

Purity

96.97

Smiles

N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(NCC(NCC([O-])=O)=O)=O)[C@H](O)C)=O)C)=O)=O)C)=O)CO)=O)CCCC[N+](C)(C)C)=O)CCCNC(N)=N)=O)C)=O)C)=O)CCCCN)=O)[C@H](O)C)=O)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)C

Molecular Formula

C87H157N30O25

Molecular Weight

2023.40

References & Citations

[1]Elizabeth T Wiles, et al. H3K27 Methylation: A Promiscuous Repressive Chromatin Mark. Curr Opin Genet Dev. 2017 Apr;43:31-37.|[2]Brian P Chadwick, et al. Multiple Spatially Distinct Types of Facultative Heterochromatin on the Human Inactive X Chromosome. Proc Natl Acad Sci U S A. 2004 Dec 14;101 (50) :17450-5.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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