H-D-cis-Hyp-OH

H-D-cis-Hyp-OH (cis-4-Hydroxy-D-proline) is a proline derivative involved in bacterial metabolic pathways and is a substrate for cis-4-hydroxy-D-proline dehydrogenase. H-D-cis-Hyp-OH is a precursor for the synthesis of conformationally constrained PNA adenine monomers and can be used to study the specificity and kinetics of D-alanine dehydrogenase[1][2].

Product Specifications

CAS Number

[2584-71-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/h-d-cis-hyp-oh.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : < 1 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

[C@H]1(NC[C@H](O)C1)C(=O)O

Molecular Formula

C5H9NO3

Molecular Weight

131.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Püschl A, et, al. Pyrrolidine PNA: a novel conformationally restricted PNA analogue. Org Lett. 2000 Dec 28;2 (26) :4161-3.|[2]Watanabe S, et, al. Characterization of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. Biosci Biotechnol Biochem. 2018 Jan;82 (1) :110-113.