DSPE-PEG-Amine, MW 1000 (ammonium)

DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

Product Specifications

CAS Number

[474922-26-4]

Product Name Alternative

DSPE-PEG-NH2, MW 1000 (ammonium)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dspe-peg-amine-mw-1000-ammonium.html

Purity

99.48

Solubility

10 mM in DMSO

Smiles

O=C(O[C@@H](COP(OCCNC(OCCOCCN)=O)([O-])=O)COC(CCCCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCCCC.[NH4+].[n]

Molecular Formula

(C2H4O) nC44H87N2O10P.NH3

Molecular Weight

1000 (Average)

Precautions

H302, H315, H319, H335

References & Citations

[1]Nagata H, et al. Preparation and Catalytic Properties of Carbonic Anhydrase Conjugated to Liposomes through a Bis-Aryl Hydrazone Bond. ACS Omega. 2023 May 16;8 (21) :18637-18652.