Cyclotraxin B acetate (1203586-72-4 free base)
Cyclotraxin B acetate is a potent and selective allosteric antagonist of the TrkB receptor (IC50 = 0.30 nM), inhibiting BDNF signaling without affecting ligand binding. It is utilized in neuroscience research to study BDNF/TrkB pathways in vitro and has demonstrated in vivo efficacy in rodent models of neuropathic pain and anxiety-related behaviors.
Product Specifications
Product Name Alternative
Cyclotraxin B acetate (1203586 72 4 free base), Cyclotraxin B acetate (1203586724 free base), Cyclotraxin B acetate (1203586-72-4 free base), TrkB, Trkreceptor, Trk receptor
Field of Research
Signal Transduction
Purity
99.42% (May vary between batches)
Solubility
DMSO:10 mM
Molecular Weight
1260.42
Storage Conditions
Keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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