2-NBDG Glucose Uptake Cell-Based Kit

2-NBDG Reagent is a green fluorescently labeled deoxyglucose analog with the same transporters (GLUTs) and similar transport kinetics as D-glucose.It is allowed to be phosphorylated by hexokinase because of a modification at the C-2 position.When it enters the cell, it is phosphorylated by hexokinase at the C-6 position to produce 2-NBDG-6-phosphate (a fluorescent derivative) . Thus the fluorescence intensity reflects the glucose uptake.

Can be used for flow cytometry and fluorescence microscopy to detect the glucose uptake viability of cells; can also be used for the evaluation and screening of drugs for glucose metabolic diseases