Human Cadherin-17 / CDH17 Protein, His Tag
Human Cadherin-17, His Tag (CA7-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Gln 23 - Met 787 (Accession # Q12864) .
Product Specifications
Background
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 86.9 kDa. The protein migrates as 95-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q12864
Expression Region
Gln 23 - Met 787
Host
HEK293
Target
Cadherin-17
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human Cadherin-17, His Tag (Cat. No. CA7-H52H3) at 1 μg/mL (100 μL/well) can bind Anti-Cadherin 17/CDH17 Antibody with a linear range of 0.0000122-0.000391 % (QC tested).
Format
Powder
Buffer
20 mM Tris, 150 mM NaCl, pH8.0
Additives
Trehalose
Molecular Weight
86.9 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CA7-H52H3.pdf
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
