Nodinitib-1

Nodinitib-1 (ML130; CID-1088438) is a NOD1 inhibitor with an IC50 of 0.56 μM.

Product Specifications

CAS Number

[799264-47-4]

Product Name Alternative

ML130; CID-1088438

UNSPSC

12352005

Hazard Statement

H302

Target

NOD-like Receptor (NLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Nodinitib-1.html

Purity

99.94

Solubility

DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

NC1=NC2=CC=CC=C2N1S(=O)(C3=CC=C(C)C=C3)=O

Molecular Formula

C14H13N3O2S

Molecular Weight

287.34

Precautions

H302

References & Citations

[1]Correa RG, et al. Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol. 2011 Jul 29;18 (7) :825-32.|[2]Hershberger PM, et al. Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway. Beilstein J Org Chem. 2013 May 8;9:900-7.