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Nodinitib-1

Product Specifications

UNSPSC Description

Nodinitib-1 (ML130;CID-1088438) is a NOD1 inhibitor with an IC50 of 0.56 μM.

Target Antigen

NOD-like Receptor (NLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Nodinitib-1.html

Purity

99.94

Solubility

DMSO : 20 mg/mL (ultrasonic;warming)

Smiles

NC1=NC2=CC=CC=C2N1S(=O)(C3=CC=C(C)C=C3)=O

Molecular Weight

287.34

References & Citations

[1]Correa RG, et al. Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol. 2011 Jul 29;18(7):825-32.|[2]Hershberger PM, et al. Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway. Beilstein J Org Chem. 2013 May 8;9:900-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-18639/Nodinitib-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18639/Nodinitib-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

799264-47-4

Available Sizes

Curated Selection

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