Nodinitib-1
Nodinitib-1 (ML130; CID-1088438) is a NOD1 inhibitor with an IC50 of 0.56 μM.
Product Specifications
CAS Number
799264-47-4
Product Name Alternative
ML130; CID-1088438
UNSPSC
12352005
Hazard Statement
H302
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Nodinitib-1.html
Purity
99.94
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
NC1=NC2=CC=CC=C2N1S(=O)(C3=CC=C(C)C=C3)=O
Molecular Formula
C14H13N3O2S
Molecular Weight
287.34
Precautions
H302
References & Citations
[1]Correa RG, et al. Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol. 2011 Jul 29;18 (7) :825-32.|[2]Hershberger PM, et al. Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway. Beilstein J Org Chem. 2013 May 8;9:900-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOD1
Available Sizes
Frequently Asked Questions
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