Noggin Recombinant Protein

Product Specifications

Product Name Alternative

SYM1, SYNS1, Noggin

UniProt

Q13253

Source

HEK293 cells

Field of Research

Cancer Biology, Cell Biology, Signal Transduction

Purity

Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .

Bioactivity

Biological activity was determined by its ability to inhibit 5.0 ng/mL of BMP - 4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 2.0 - 3.0 ng/mL of Noggin.

Form

Lyophilized

Storage Conditions

The lyophilized Noggin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Noggin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Noggin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Notes

For research use only.

NCBI Accession Number

NP_005441.1

AA Sequence

QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC