Noggin Recombinant Protein

Biological activity was determined by its ability to inhibit 5.0 ng/mL of BMP - 4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 1.0 - 2.0 ng/mL of Noggin.

The lyophilized Noggin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Noggin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Noggin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC