Leptin Recombinant Protein
Leptin Recombinant Protein
Product Specifications
Product Name Alternative
Ob, obese, Ob, Leptin, Obesity factor
UniProt
P41160
Source
E. coli
Field of Research
Metabolism Research
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 μg Leptin/gm of body weight for 14 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline - treated controls
Form
Lyophilized
Storage Conditions
The lyophilized Leptin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Leptin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Leptin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_032519.1
AA Sequence
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
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