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Leptin Recombinant Protein

Leptin Recombinant Protein

Product Specifications

Product Name Alternative

Ob, obese, Ob, Leptin, Obesity factor

UniProt

P41160

Source

E. coli

Field of Research

Metabolism Research

Purity

Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .

Bioactivity

Murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 μg Leptin/gm of body weight for 14 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline - treated controls

Form

Lyophilized

Storage Conditions

The lyophilized Leptin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Leptin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Leptin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Notes

For research use only.

NCBI Accession Number

NP_032519.1

AA Sequence

MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC

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