BAFF Recombinant Protein
BAFF Recombinant Protein
Product Specifications
Product Name Alternative
BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B, Tumor Necrosis Factor Ligand Superfamily Member 13B
UniProt
P25311
Tag
Fc Tag
Source
CHO cells
Field of Research
Immunology & Inflammation
Concentration
0.1mg/ml after reconstitution.
Purity
>95% (SDS-PAGE) . Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza) .
Bioactivity
Rescues the production of mature follicular and marginal zone B cells. - in vitro: Addition of 1-100 ng/ml of Fc-BAFF induces B cell survival in a dose-dependent manner. - in vivo: Fc-BAFF treatment rescues mature B cell development in BAFF deficient mice. Mice are injected at day 0 with 100 ug Fc-BAFF i.v. and at day 14 with 50 ug Fc-BAFF i.p.
Form
Lyophilized
Storage Conditions
Stable for at least 6 months after receipt when stored at -20°C.
Notes
For research use only.
Applications Notes
This recombinant proteins is for research use only.
NCBI Accession Number
Q9Y275
Preservative
Contains PBS. Reconstitute with 100 μl sterile water.
AA Sequence
The receptor-binding domain of human BAFF (aa 136-285) is fused at the N-terminus to the Fc portion of human IgG1.
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