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CD152 [CTLA-4] Recombinant Protein

CD152 [CTLA-4] Recombinant Protein

Product Specifications

Product Name Alternative

CTLA-4

UniProt

P60568

Tag

Fc Tag

Source

NS1 cells

Field of Research

Immunology & Inflammation

Purity

>98% (SDS-PAGE) . Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza) .

Bioactivity

Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely.

Form

Lyophilized

Storage Conditions

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Notes

For research use only.

Applications Notes

This recombinant proteins is for research use only.

NCBI Accession Number

NP_033973

Preservative

Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 1mg/ml in sterile water. Add 1X PBS to the desired protein concentration.

AA Sequence

The extracellular domain of mouse CD152 [CTLA-4] (aa 38-160) is fused to the N-terminus of the Fc region of mouse IgG2a.

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