IL-2 non-lytic Recombinant Protein
IL-2 non-lytic Recombinant Protein
Product Specifications
Product Name Alternative
Interleukin-2, Aldesleukin
UniProt
Q9GZX6
Tag
Fc Tag
Source
NS1 cells
Field of Research
Immunology & Inflammation
Purity
>98% (SDS-PAGE) . Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza) .
Bioactivity
Specific Activity: 1-1.5 x106 Units/mg, measured using CTLL indicator cells. Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic autoimmunity in nonobese diabetic mice.
Form
Lyophilized
Storage Conditions
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Notes
For research use only.
Applications Notes
This recombinant proteins is for research use only.
NCBI Accession Number
NP_032392
Preservative
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
AA Sequence
The extracellular domain of mouse IL-2 (aa 21-169) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
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