What is the catalog number for IL-15 mutant Recombinant Protein (biotin)?

The catalog number for IL-15 mutant Recombinant Protein (biotin) is orb1229913.

What sizes are available for IL-15 mutant Recombinant Protein (biotin)?

IL-15 mutant Recombinant Protein (biotin) is available in the following size(s): 1 Vial.

Is IL-15 mutant Recombinant Protein (biotin) in stock?

IL-15 mutant Recombinant Protein (biotin) is currently made to order / not held in immediate stock. Contact us for lead time.

IL-15 mutant Recombinant Protein (biotin)

Product Specifications

Product Name Alternative

Interleukin-15

UniProt

O88516

Tag

Fc Tag

Source

CHO cells

Field of Research

Immunology & Inflammation

Purity

>98% (SDS-PAGE) . Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza) .

Bioactivity

This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT-signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain.

Form

Lyophilized

Storage Conditions

Stable for at least 6 months after receipt when stored at +4°C.

Notes

For research use only.

Applications Notes

This recombinant proteins is for research use only.

NCBI Accession Number

NP_751914

Preservative

In PBS and 0.09% sodium azide.

AA Sequence

The extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of mouse IgG2a.