Vapendavir (diphosphate)
Product Specifications
UNSPSC Description
Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].
Target Antigen
Enterovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vapendavir-diphosphate.html
Purity
98.75
Solubility
DMSO : 6.75 mg/mL (ultrasonic)
Smiles
CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12.OP(O)(O)=O.OP(O)(O)=O
Molecular Weight
578.45
References & Citations
[1]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.|[2]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.Norwegian University of Science and Technology. 2023 May.|ACS Infect Dis. 2020 May 8;6(5):882-890.|SSRN. 2024 Apr 19.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106254A/Vapendavir-diphosphate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106254A/Vapendavir-diphosphate-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1198151-75-5
Available Sizes
Curated Selection
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